Definition of dideoxyinosine in English:

dideoxyinosine

(also DDI, ddI)

noun ˌdʌɪdɪɒksɪˈɪnəʊsiːnˌdīdēˌäksēˈinəsēn

mass nounMedicine

A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside.
〔医〕（用于治疗艾滋病的）地达诺新双脱氧次黄（嘌呤核）苷
Example sentencesExamples
- A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.
- In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
- The drugs ZDV and 3TC are manufactured by GlaxoSmithKline; ddI, d4T and EFV are manufactured by Bristol-Myers Squibb Company; and NFV is manufactured by Pfizer.
- Several analogs are used to interfere with the replication of HIV, such as AZT and ddI (dideoxyinosine).
- We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT.

Origin

1970s: from di-¹ 'two' + deoxy- (in the sense 'that has lost oxygen') + inosine.

Definition of dideoxyinosine in US English:

dideoxyinosine

(also ddI, DDI)

nounˌdīdēˌäksēˈinəsēn

Medicine

A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a purine nucleoside.
〔医〕（用于治疗艾滋病的）地达诺新双脱氧次黄（嘌呤核）苷
Example sentencesExamples
- In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
- The drugs ZDV and 3TC are manufactured by GlaxoSmithKline; ddI, d4T and EFV are manufactured by Bristol-Myers Squibb Company; and NFV is manufactured by Pfizer.
- A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.
- Several analogs are used to interfere with the replication of HIV, such as AZT and ddI (dideoxyinosine).
- We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT.

Origin

1970s: from di- ‘two’ + deoxy- (in the sense ‘that has lost oxygen’) + inosine.

单词	dideoxyinosine
释义	Definition of dideoxyinosine in English: dideoxyinosine (also DDI, ddI) noun ˌdʌɪdɪɒksɪˈɪnəʊsiːnˌdīdēˌäksēˈinəsēn mass nounMedicine A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside. 〔医〕（用于治疗艾滋病的）地达诺新双脱氧次黄（嘌呤核）苷 Example sentencesExamples A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb. In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died. The drugs ZDV and 3TC are manufactured by GlaxoSmithKline; ddI, d4T and EFV are manufactured by Bristol-Myers Squibb Company; and NFV is manufactured by Pfizer. Several analogs are used to interfere with the replication of HIV, such as AZT and ddI (dideoxyinosine). We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT. Origin 1970s: from di-¹ 'two' + deoxy- (in the sense 'that has lost oxygen') + inosine. Definition of dideoxyinosine in US English: dideoxyinosine (also ddI, DDI) nounˌdīdēˌäksēˈinəsēn Medicine A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analog of a purine nucleoside. 〔医〕（用于治疗艾滋病的）地达诺新双脱氧次黄（嘌呤核）苷 Example sentencesExamples In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died. The drugs ZDV and 3TC are manufactured by GlaxoSmithKline; ddI, d4T and EFV are manufactured by Bristol-Myers Squibb Company; and NFV is manufactured by Pfizer. A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb. Several analogs are used to interfere with the replication of HIV, such as AZT and ddI (dideoxyinosine). We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT. Origin 1970s: from di- ‘two’ + deoxy- (in the sense ‘that has lost oxygen’) + inosine.
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