A sequence of nucleotide triplets that begins with an initiation codon but has no a termination codon, and is therefore a possible polypeptide coding sequence; abbreviated ORF.
Origin
1970s; earliest use found in Nucleic Acids Research.
Definition of open reading frame in US English:
open reading frame
noun
A sequence of nucleotide triplets that begins with an initiation codon but has no a termination codon, and is therefore a possible polypeptide coding sequence; abbreviated ORF.
Origin
1970s; earliest use found in Nucleic Acids Research.